Publications



Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease


Karin A Ziegler, Andrea Ahles, Anne Dueck, Dena Esfandyari, Pauline Pichler, Karolin Weber, Stefan Kotschi, Alexander Bartelt, Inga Sinicina, Matthias Graw, Heinrich Leonhardt, Ludwig T Weckbach, Steffen Massberg, Martina Schifferer, Mikael Simons, Luciano Hoeher, Jie Luo, Ali Ertürk, Gabriele G Schiattarella, Yassine Sassi, Thomas Misgeld, Stefan Engelhardt

Science. 2023, 381,285-290.

Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage


Christina Beck, Deepak Ramanujam, Paula Vaccarello, Florenc Widenmeyer, Martin Feuerherd, Cho-Chin Cheng, Anton Bomhard, Tatiana Abikeeva, Julia Schädler, Jan-Peter Sperhake, Matthias Graw, Seyer Safi, Hans Hoffmann, Claudia A. Staab-Weijnitz, Roland Rad, Ulrike Protzer, Thomas Frischmuth, Stefan Engelhardt

Nat Commun. 2023. 14, 4564.

Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus


Fangfang Zhang, Anna B Meier, Daniel Sinnecker, Stefan Engelhardt, Peter Lipp, Karl-Ludwig Laugwitz, Tatjana Dorn, Alessandra Moretti

Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing


Palgit-S. Kogan, Felix Wirth, Archana Tomar, Jonatan Darr, Raffaele Teperino, Harald Lahm, Martina Dreßen, Nazan Puluca, Zhong Zhang, Irina Neb, Nicole Beck, Tatjana Luzius, Luis de la Osa de la Rosa, Kathrin Gärtner, Corinna Hüls, Reinhard Zeidler, Deepak Ramanujam, Stefan Engelhardt, Catharina Wenk, Lesca M. Holdt, Mimmi Mononen, Makoto Sahara, Julie Cleuziou, Jürgen Hörer, Rüdiger Lange, Markus Krane & Stefanie A. Doppler

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver


Thorsten Kaltenbacher, Jessica Löprich, Roman Maresch, Julia Weber, Sebastian Müller, Rupert Oellinger, Nina Groß, Joscha Griger, Niklas de Andrade Krätzig, Petros Avramopoulos, Deepak Ramanujam, Sabine Brummer, Sebastian A. Widholz, Stefanie Bärthel, Chiara Falcomatà, Anja Pfaus, Ahmed Alnatsha, Julia Mayerle, Marc Schmidt-Supprian, Maximilian Reichert, Günter Schneider, Ursula Ehmer, Christian J. Braun, Dieter Saur, Stefan Engelhardt, Roland Rad

Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling


Melina Lopez, Pedro F. Malacarne, Deepak P. Ramanujam, Timothy Warwick, Niklas Müller, Jiong Hu, Matthias Dewenter, Andreas Weigert, Stefan Günther, Ralf Gilsbach, Stefan Engelhardt, Ralf P. Brandes, Flávia Rezende

MicroRNAs as therapeutic targets in cardiovascular disease


Bernhard Laggerbauer, Stefan Engelhardt

Nicht kodierende Ribonukleinsäure im kardiovaskulären System


S. Engelhardt, S. Dimmeler, C. Heim, C. Bär, T. Böttger, R. Boon, R. P. Brandes, T. Braun, A. Dueck, J. Gagneur, P.Grote, L.M. Holdt, N. Jaé , J. Krishnan, C. Kupatt, K.-L. Laugwitz, M. S. Leisegang, L. Maegdefessel, T. Meitinger, A. Moretti, M. Müller-McNicoll, M. Sattler, A. Schnieke, M. Schulz, H. Schunkert, H. Schwalbe, D. Teupser, T. Thum, C.Weber, I. Wittig, K. Zarnack

MicroRNA-365 regulates human cardiac action potential duration


Esfandyari D, Idrissou BMG, Hennis K, Avramopoulos P, Dueck A, El-Battrawy I, Grüter L, Meier MA, Näger AC, Ramanujam D, Dorn T, Meitinger T, Hagl C, Milting H, Borggrefe M, Fenske S, Biel M, Dendorfer A, Sassi Y, Moretti A, Engelhardt S

The long non-coding RNA NRON promotes the development of cardiac hypertrophy in the murine heart


Jeannine Hoepfner, Julia Leonardy, Dongchao Lu, Kevin Schmidt, Hannah J Hunkler, Sinje Biß, Ariana Foinquinos, Ke Xiao, Kumarswamy Regalla, Deepak Ramanujam, Stefan Engelhardt, Christian Bär, Thomas Thum